Clinical Report
Prosthetic and implant rehabilitation in hypohidrotic ectodermal dysplasia: A 13-year follow-up

https://doi.org/10.1016/j.prosdent.2025.07.015Get rights and content

Abstract

This clinical report describes the long-term oral rehabilitation of a male patient with hypohidrotic ectodermal dysplasia (HED), a congenital disorder characterized by hypodontia, hypotrichosis, and hypohidrosis. At age 3, the patient presented with only 2 conical teeth and total edentulism in the remaining arches. A multidisciplinary, staged treatment plan was implemented from early childhood to adulthood that included preserving erupted teeth, interim prostheses, orthodontics, and early strategic implant placement adapted to craniofacial growth. Initial mandibular implants were placed at age 8, followed by additional implants and prostheses over time. Definitive rehabilitation at age 18 consisted of computer-aided design and computer-aided manufacture (CAD-CAM) screw-retained prostheses and ceramic restorations. At the 1-year follow-up, esthetics and function were stable.

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Section snippets

SUMMARY

The transition from conventional to digital workflows in prosthodontics has reshaped complete arch implant rehabilitation. Traditional protocols require multiple analog steps, including cast fabrication, mounting, and verification, which may compromise efficiency.1 Previous hybrid intraoral–extraoral scanning approaches have provided improvements but still required physical verification steps and cast fabrication.2 Available fully digital protocols often rely on reference screws and multiple

DISCUSSION

The RDC 2.0 workflow is fully digital and eliminates the need for physical casts, mounting procedures, or intraoral conversion immediately after implant placement.15, 16 By digitally articulating intraorally captured data, the restorative workflow becomes simplified and reproducible.17, 18 This approach reduces chair time, accelerates laboratory fabrication, and maintains accuracy in implant position, soft-tissue morphology, and occlusal registration.19 Errors are minimized by reducing the

PATIENT CONSENT

Written informed consent was obtained from the patient for publication of this case and the accompanying images, in accordance with the policies of the Journal and the Declaration of Helsinki.

Intellectual Property

We have complied with the guidelines regarding intellectual property rights, ensuring no publication barriers concerning intellectual property, in accordance with the policies of our respective institutions.

Authorship

All listed contributors qualify as authors according to the International Committee of Medical Journal Editors (ICMJE) guidelines, having made substantial contributions to the manuscript and accepting responsibility for its content's accuracy and integrity.

Communication with the Editorial Office

The Corresponding Author identified on the title page serves as the sole contact for the editorial process, responsible for liaising with the editorial office and xco-authors. The provided email address for correspondence is actively linked to the Corresponding Author's account, prepared to receive messages from the journal's editorial team.

Consent for Publication

With the signatures below, we, the undersigned authors, concur with the statements made herein and approve the manuscript for publication.

Research Ethics

Consent for the publication of any identifying information was obtained from all participants or their legal guardians, adhering to ethical standards.

Acknowledgments

The author gratefully acknowledges the invaluable inspiration and guidance received from mentors and educators who have shaped his professional journey over the years. Special appreciation is extended to Dr Stephen Rosenstiel, whose insightful editorial guidance and mentorship have been instrumental in refining this article and previous publications, significantly enhancing their clarity and scholarly impact. Deepest thanks are also offered to Drs Dennis Tarnow, Giovanni Zucchelli, Michael

References (23)

  • F.L. Vieira et al.

    Intraoral scanning versus conventional methods for complete-arch implant prostheses

    Appl Sci

    (2025)

    • Cited by (0)

    This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
    We hereby affirm that there are no conflicts of interest associated with this manuscript. No financial assistance was received that could have influenced the outcomes of this research, maintaining the research's integrity and impartiality.
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